Document Type
Article
Publication Date
2-1996
Abstract
Anabaptist history is a chronicle of repeated migrations, fissions, and fusions of various subgroups. The effects of these events should be evident in the population biology of the Anabaptist groups. No prior genetic studies have included the polymorphic and highly informative immunoglobulin markers. Here, 685 serum samples representing 1 Amish and 3 Mennonite community samples (7 congregations) were studied for immunoglobulin allotypes. The haplotypes IGHG*F B, IGHG*A,Z G, and IGHG*A,X,Z G range in frequency from 0.542 to 0.765, 0.123 to 0.290, and 0.075 to 0.170, respectively. IGK*1 frequencies range from 0.035 to 0.077, All frequencies are within expected ranges for central and western European population samples, There was considerable intergroup variability among the Anabaptist samples that was statistically significant x29 = 22.63, 0.005 < p < 0.01), Principal component analyses, including the immunoglobulin allotype frequencies and published data on ABO, MN, and Rhesus (Dd) markers, demonstrate that the Mennonite congregation samples with close historical ties group together acid are distinct from the Amish and Meridian congregation samples.
Publication Title
Human Biology
Volume
68
Issue
1
First Page
45
Last Page
62
Required Publisher's Statement
Published by: Wayne State University Press
Stable URL: http://www.jstor.org/stable/41465452
Recommended Citation
Stevenson, Joan C.; Everson, Phillip Mark; Martin, K.; Crawford, Michael H.; and Schanfield, Moses S., "Immunoglobulin Haplotype Frequencies in Anabaptist Population Samples: Kansas and Nebraska Mennonites and Indiana Amish" (1996). Anthropology Faculty and Staff Publications. 7.
https://cedar.wwu.edu/anthropology_facpubs/7
Subjects - Topical (LCSH)
Mennonites--Kansas--Case studies; Mennonites--Nebraska--Case studies; Amish--Indiana--Case studies; Immunoglobulin allotypes
Geographic Coverage
Kansas; Nebraska; Indiana
Genre/Form
articles
Type
Text
Language
English
Format
application/pdf
