Poster Title

Synthetic Studies on Guaipyridine Alkaloids: Intramolecular Heck Approach

Co-Author(s)

Patrick Shelton, James Vyvyan

Research Mentor(s)

James Vyvyan

Affiliated Department

Chemistry

Sort Order

49

Start Date

14-5-2015 10:00 AM

End Date

14-5-2015 2:00 PM

Document Type

Event

Abstract

Guaipyridine alkaloids are a rare family of natural products characterized by a pyridine-fused cycloheptane structure. Examples include cananodine, isolated from Cananga odorata, and the rupestines, isolated from Artemesia rupestris. We have previously explored the creation of the pyridine-fused cycloheptane core using an intramolecular epoxide opening. Here we present our results using an intramolecular Heck coupling approach to the seven-membered ring of the guaipyridine targets.

Rights

Copying of this document in whole or in part is allowable only for scholarly purposes. It is understood, however, that any copying or publication of this documentation for commercial purposes, or for financial gain, shall not be allowed without the author's written permission.

Language

English

Format

application/pdf

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May 14th, 10:00 AM May 14th, 2:00 PM

Synthetic Studies on Guaipyridine Alkaloids: Intramolecular Heck Approach

Chemistry

Guaipyridine alkaloids are a rare family of natural products characterized by a pyridine-fused cycloheptane structure. Examples include cananodine, isolated from Cananga odorata, and the rupestines, isolated from Artemesia rupestris. We have previously explored the creation of the pyridine-fused cycloheptane core using an intramolecular epoxide opening. Here we present our results using an intramolecular Heck coupling approach to the seven-membered ring of the guaipyridine targets.