Poster Title

Metal Mixture Toxicity to Lettuce Seedlings (Lactuca sativa)

Co-Author(s)

Amanda M. Smith, Colton Charlton, Eric J. Lawrence, Ruth M. Sofield

Research Mentor(s)

Ruth Sofield

Affiliated Department

Environmental Sciences

Sort Order

49

Start Date

17-5-2017 12:00 PM

End Date

17-5-2017 3:00 PM

Document Type

Event

Abstract

Metals are often found in the environment in mixtures. There is limited metal mixture data for management models used to assess the impacts of chemicals in the environment. In this project we are testing the acute toxicity of metal mixtures to Lactuca sativa (lettuce) and using the results to characterize mixture interactions. The mixtures are binary combinations of the following metals: iron, copper, zinc, aluminum, and cadmium. We are looking for effects where the combination of two metals are either more toxic (synergistic) or less toxic (antagonistic) than expected based on additivity. To date, binary combinations of iron and cadmium, iron and zinc, iron and copper, and cadmium and zinc are antagonistic, which is not as expected if the toxic mechanism is the same for each metal. Studying mixture toxicity will lead to better understanding of the mechanisms of metal toxicity that determine the differences in mixture effects. Ultimately, this can lead to better informed decision making when assessing the risk of metals in the environment and creating regulations.

Comments

Outstanding Poster Award Recipient

Rights

Copying of this document in whole or in part is allowable only for scholarly purposes. It is understood, however, that any copying or publication of this documentation for commercial purposes, or for financial gain, shall not be allowed without the author's written permission.

Language

English

Format

application/pdf

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May 17th, 12:00 PM May 17th, 3:00 PM

Metal Mixture Toxicity to Lettuce Seedlings (Lactuca sativa)

Environmental Sciences

Metals are often found in the environment in mixtures. There is limited metal mixture data for management models used to assess the impacts of chemicals in the environment. In this project we are testing the acute toxicity of metal mixtures to Lactuca sativa (lettuce) and using the results to characterize mixture interactions. The mixtures are binary combinations of the following metals: iron, copper, zinc, aluminum, and cadmium. We are looking for effects where the combination of two metals are either more toxic (synergistic) or less toxic (antagonistic) than expected based on additivity. To date, binary combinations of iron and cadmium, iron and zinc, iron and copper, and cadmium and zinc are antagonistic, which is not as expected if the toxic mechanism is the same for each metal. Studying mixture toxicity will lead to better understanding of the mechanisms of metal toxicity that determine the differences in mixture effects. Ultimately, this can lead to better informed decision making when assessing the risk of metals in the environment and creating regulations.