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Date Permissions Signed

11-15-2013

Date of Award

2013

Document Type

Masters Thesis

Degree Name

Master of Science (MS)

Department

Chemistry

First Advisor

Emory, Steven R.

Second Advisor

Rider, David A. (Materials scientist)

Third Advisor

Patrick, David L.

Abstract

While the medical field incorporates various imaging methods for diagnosis and treatment, there is a need for continual development of real-time in vivo imaging techniques in this field. A surface-enhanced Raman scattering (SERS) based fiber optic sensor is reported. An optical fiber was coated in gold nanoparticles, capable of Raman scattering. SERS active molecules were adsorbed onto the gold nanoparticle film, and SERS spectra obtained. Using 4-mercaptopyridine as a SERS reporter molecule, the chemical environment surrounding the probe was determined by the analysis of the pH sensitive SERS spectra. The methods of preparation and characterization of the SERS-based fiber sensors are presented, as well as an analysis of the optimal geometry for the tip of the probe.

Type

Text

Publisher

Western Washington University

OCLC Number

864437975

Digital Format

application/pdf

Genre/Form

Academic theses

Language

English

Rights

Copying of this thesis in whole or in part is allowable only for scholarly purposes. It is understood, however, that any copying or publication of this thesis for commercial purposes, or for financial gain, shall not be allowed without the author's written permission.

Included in

Chemistry Commons

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