Metallic nanomaterial decorated silk films as flexible, biocompatible SERS substrates

Research Mentor(s)

Ying Bao and Amanda Murphy

Description

Metal nanomaterials, including gold and silver, have obtained tremendous attention due to their fascinating optical properties. Such properties make them great candidates for improving the development of optical sensors. For example, surface-enhanced Raman scattering-based sensors are one of the most well-known and popular sensors in recent research due to their ability to detect and enhance signals of minute target analytes. And silk films are used as a platform due to their properties as mechanically stable, biocompatible conducting polymers. This work presents effective methods to fabricate biocompatible metallic nanomaterial decorated silk films using gold and silver. The films are first modified to hold a positive surface charge, which is followed by a seed-mediated electroless deposition of select metals. Scanning electron microscopy was used to characterize the morphology of the resulted thin films. The results indicate that the distribution and morphology of metallic nanomaterial can be controlled, providing promising potential for developing novel biosensors.

Document Type

Event

Start Date

May 2022

End Date

May 2022

Location

Carver Gym (Bellingham, Wash.)

Department

CSE - Materials Science

Genre/Form

student projects; posters

Type

Image

Rights

Copying of this document in whole or in part is allowable only for scholarly purposes. It is understood, however, that any copying or publication of this document for commercial purposes, or for financial gain, shall not be allowed without the author’s written permission.

Language

English

Format

application/pdf

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May 18th, 9:00 AM May 18th, 5:00 PM

Metallic nanomaterial decorated silk films as flexible, biocompatible SERS substrates

Carver Gym (Bellingham, Wash.)

Metal nanomaterials, including gold and silver, have obtained tremendous attention due to their fascinating optical properties. Such properties make them great candidates for improving the development of optical sensors. For example, surface-enhanced Raman scattering-based sensors are one of the most well-known and popular sensors in recent research due to their ability to detect and enhance signals of minute target analytes. And silk films are used as a platform due to their properties as mechanically stable, biocompatible conducting polymers. This work presents effective methods to fabricate biocompatible metallic nanomaterial decorated silk films using gold and silver. The films are first modified to hold a positive surface charge, which is followed by a seed-mediated electroless deposition of select metals. Scanning electron microscopy was used to characterize the morphology of the resulted thin films. The results indicate that the distribution and morphology of metallic nanomaterial can be controlled, providing promising potential for developing novel biosensors.