Conductive polymer, Peptide, Hydrogel, Beta-sheet
Here, we have taken a bottom-up approach to confer multidimensional structure to conductive polymers by attaching thiophene monomers to peptides predicted to self-assemble into a biomimetic, fibrous nanostructure. A library of 12 peptides containing covalently attached thiophene-based monomers was synthesized. Peptide sequences that resulted in self-assembly and hydrogel formation in aqueous media were identified and the physical and electrical properties were characterized. The resulting hybrid materials have conductivities in the range of 10-2-10-3 S/cm, and possess moduli in the range of several tissue types, making them potential candidates for use in biomedical electronic applications.
James, Ellie I., "Exploration of Peptide-Thiophene Hybrids as Self-Assembling Conductive Hydrogels" (2018). WWU Honors Program Senior Projects. 92.
student projects; term papers
Copying of this document in whole or in part is allowable only for scholarly purposes. It is understood, however, that any copying or publication of this document for commercial purposes, or for financial gain, shall not be allowed without the author’s written permission.