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Date of Award
Master of Science (MS)
Emory, Steven R.
Rider, David A. (Materials scientist)
Patrick, David L.
While the medical field incorporates various imaging methods for diagnosis and treatment, there is a need for continual development of real-time in vivo imaging techniques in this field. A surface-enhanced Raman scattering (SERS) based fiber optic sensor is reported. An optical fiber was coated in gold nanoparticles, capable of Raman scattering. SERS active molecules were adsorbed onto the gold nanoparticle film, and SERS spectra obtained. Using 4-mercaptopyridine as a SERS reporter molecule, the chemical environment surrounding the probe was determined by the analysis of the pH sensitive SERS spectra. The methods of preparation and characterization of the SERS-based fiber sensors are presented, as well as an analysis of the optimal geometry for the tip of the probe.
Western Washington University
Copying of this thesis in whole or in part is allowable only for scholarly purposes. It is understood, however, that any copying or publication of this thesis for commercial purposes, or for financial gain, shall not be allowed without the author's written permission.
Wellner, Elizabeth C. (Elizabeth Cecilia), "Development of surface-enhanced Raman based sensors" (2013). WWU Graduate School Collection. 312.