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Date Permissions Signed


Date of Award


Document Type

Masters Thesis

Degree Name

Master of Education (MEd)


Health and Human Development

First Advisor

Brilla, Lorraine R., 1955-

Second Advisor

Knutzen, Kathleen

Third Advisor

Suprak, David N. (David Nathan)


This purpose of this study was to evaluate the effects of four weeks of magnesiumcreatine chelate (MgCr), alkaline creatine (AlkCr), and placebo (P) on delayed onset muscle soreness (DOMS). Subjects were 36 young (18-24 years old), healthy, recreationally active individuals, randomly assigned to groups. Double blind supplementation was dextran (P), 5 g creatine, 400 mg (MgCr), and 5 g creatine plus soda ash (AlkCr) per day. Subjects exercised on an eccentric training machine with foot pedals yielding force that was resisted eccentrically. Peak eccentric force was obtained at 35 cycles per minute. Subjects maintained 65% of the peak eccentric force, for five minutes of continuous work. They reported muscle soreness scores corresponding to a visual analog scale with scores from 1, normal, to 10, very, very sore at 12, 24, 48, 60, and 72 hours post exercise. Repeated measures ANOVA was applied. The creatine groups did have significant main effects of time in DOMS on a visual analog scale after 5 minutes of eccentric exercise (p<0.05). There were no significant effects between creatine groups (p<0.05). Within group time effects were observed at 12, 24, and 36 hour intervals for AlkCr and at 12 hour intervals up to the 60 hours for MgCr, with DOMS scores lower following intervention. Pre intervention 12- and 72-hour soreness scores were P: 6.0±1.6, 3.6±2.3; MgCr: 5.0±2.9, 3.5±2.3; AlkCr: 4.5±1.9, 3.9±1.9 and post intervention 12- and 72-hour soreness scores were P: 4.7±1.5, 2.7±1.2; MgCr: 3.2±1.6, 2.3±1.6; AlkCr: 3.5±2.0, 2.5±1.9. Creatine supplementation regimens for four weeks ameliorated DOMS perception following 5-minutes of eccentric activity. The mechanism for the findings remains to be elucidated, but may be related to anti-inflammatory effects.





Western Washington University

OCLC Number


Subject – LCSH

Pain--Alternative treatment--Evaluation; Creatine; Magnesium; Myalgia




masters theses




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