Faculty Advisor

Ed Weber Dr Froylan Sifuentes

Document Type

Article

Publication Date

Summer 2025

Keywords

Internship

Abstract

Upon review, the current Hanford Primary Remediation Goals (PRGs) are revealed to be based on ineffective endpoints describing outdated studies designed for agricultural purposes. Our results using EC25s demonstrated the need to update the basis for deriving plant endpoints based on an ongoing risk assessment at Hanford. This highlights the necessity of aligning experimental data with regulatory frameworks to ensure accurate risk characterization. Ultimately, translating experimental data into usable risk assessment metrics requires consistency between research methodologies and regulatory needs. The SSD approach requires numerous rich and diverse toxicology studies standardized to a single endpoint type, which is not a reality today. This data review informs the recommendation of EC25s as standard to inform PRGs for plant data.

Type

Text

Rights

Copying of this document in whole or in part is allowable only for scholarly purposes. It is understood, however, that any copying or publication of this document for commercial purposes, or for financial gain, shall not be allowed without the author’s written permission.

Language

English

Format

application/pdf

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