Preparation of Heterocycles by Gold Catalyzed Cyclizations of Propargyl Ethers and Sulfides
Research Mentor(s)
Vyvyan, James R.
Description
Oxygen heterocycles are synthesized by the intramolecular cyclization of substrates catalyzed by gold. One of the goals of this project was to also synthesize sulfur heterocycles. Many cyclization precursors have been formed from substituted aromatic thiols and alkynes. By investigating the effect of gold on intramolecular cyclizations, we can extend our studies to the varying substituents and their impact on the cyclization.
Document Type
Event
Start Date
16-5-2018 9:00 AM
End Date
16-5-2018 12:00 PM
Department
Chemistry
Genre/Form
student projects, posters
Subjects – Topical (LCSH)
Gold; Organogold compounds; Oxygen; Homogeneous catalysis
Type
Image
Rights
Copying of this document in whole or in part is allowable only for scholarly purposes. It is understood, however, that any copying or publication of this document for commercial purposes, or for financial gain, shall not be allowed without the author’s written permission.
Language
English
Format
application/pdf
Preparation of Heterocycles by Gold Catalyzed Cyclizations of Propargyl Ethers and Sulfides
Oxygen heterocycles are synthesized by the intramolecular cyclization of substrates catalyzed by gold. One of the goals of this project was to also synthesize sulfur heterocycles. Many cyclization precursors have been formed from substituted aromatic thiols and alkynes. By investigating the effect of gold on intramolecular cyclizations, we can extend our studies to the varying substituents and their impact on the cyclization.