Event Title

Preparation of Heterocycles by Gold Catalyzed Cyclizations of Propargyl Ethers and Sulfides

Research Mentor(s)

James Vyvyan

Description

Oxygen heterocycles are synthesized by the intramolecular cyclization of substrates catalyzed by gold. One of the goals of this project was to also synthesize sulfur heterocycles. Many cyclization precursors have been formed from substituted aromatic thiols and alkynes. By investigating the effect of gold on intramolecular cyclizations, we can extend our studies to the varying substituents and their impact on the cyclization.

Document Type

Event

Start Date

16-5-2018 9:00 AM

End Date

16-5-2018 12:00 PM

Location

Chemistry

Rights

Copying of this document in whole or in part is allowable only for scholarly purposes. It is understood, however, that any copying or publication of this document for commercial purposes, or for financial gain, shall not be allowed without the author’s written permission.

Language

English

Format

application/pdf

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May 16th, 9:00 AM May 16th, 12:00 PM

Preparation of Heterocycles by Gold Catalyzed Cyclizations of Propargyl Ethers and Sulfides

Chemistry

Oxygen heterocycles are synthesized by the intramolecular cyclization of substrates catalyzed by gold. One of the goals of this project was to also synthesize sulfur heterocycles. Many cyclization precursors have been formed from substituted aromatic thiols and alkynes. By investigating the effect of gold on intramolecular cyclizations, we can extend our studies to the varying substituents and their impact on the cyclization.