Homogenous Catalysts for the Conversion of Epoxides to Alcohols
Research Mentor(s)
Scheuermann, Margaret Louise
Description
The formation of an alcohol from an epoxide requires the cleavage of a C–O bond. The resulting product regioisomer is determined by which of the C–O bonds is cleaved and is generally substrate controlled. To date there are few examples of substrates where simply changing the catalyst can reverse the regioselectivity. Our efforts toward the use of homogeneous catalysts to control the regioselectivity of C–O bond cleavage in epoxides will be presented.
Document Type
Event
Start Date
17-5-2018 12:00 AM
End Date
17-5-2018 12:00 AM
Department
Chemistry
Genre/Form
student projects, posters
Subjects – Topical (LCSH)
Catalysis; Alcohols; Epoxy compounds
Type
Image
Rights
Copying of this document in whole or in part is allowable only for scholarly purposes. It is understood, however, that any copying or publication of this document for commercial purposes, or for financial gain, shall not be allowed without the author’s written permission.
Language
English
Format
application/pdf
Homogenous Catalysts for the Conversion of Epoxides to Alcohols
The formation of an alcohol from an epoxide requires the cleavage of a C–O bond. The resulting product regioisomer is determined by which of the C–O bonds is cleaved and is generally substrate controlled. To date there are few examples of substrates where simply changing the catalyst can reverse the regioselectivity. Our efforts toward the use of homogeneous catalysts to control the regioselectivity of C–O bond cleavage in epoxides will be presented.