Presentation Abstract
Genetic and phylogenetic analyses of Vibrio parahaemolyticus (Vp) strains isolated from the U.S. Pacific Northwest demonstrate that clinical isolates are genetically distinct from the environmental isolates. Several environmental isolates are clonally related to strains that have been responsible for Vp-related illnesses world-wide (the pandemic complex) but have not been responsible for illnesses in the Pacific Northwest. While both clinical and a significant proportion of environmental isolates encode one of the putative virulence markers, the thermostable direct hemolysin (tdh), clinical isolates also encoded a second virulence marker, the tdh-related hemolysin (trh). Our findings suggest that V. parahaemolyticus isolates from the Pacific Northwest encoding trh are more likely to be pathogenic than isolates encoding tdh alone.
Session Title
Session S-08A: Harmful Algal Blooms, Climate, Shellfish, and Public Health - Emerging Issues in a Changing World
Conference Track
Harmful Algal Blooms and Shellfish
Conference Name
Salish Sea Ecosystem Conference (2014 : Seattle, Wash.)
Document Type
Event
Start Date
2-5-2014 8:30 AM
End Date
2-5-2014 10:00 AM
Location
Room 615-616-617
Genre/Form
conference proceedings; presentations (communicative events)
Contributing Repository
Digital content made available by University Archives, Heritage Resources, Western Libraries, Western Washington University.
Subjects – Topical (LCSH)
Vibrio parahaemolyticus--Northwest, Pacific--Genetics; Vibrio parahaemolyticus--Northwest, Pacific--Variation
Geographic Coverage
Salish Sea (B.C. and Wash.); Northwest, Pacific
Rights
This resource is displayed for educational purposes only and may be subject to U.S. and international copyright laws. For more information about rights or obtaining copies of this resource, please contact University Archives, Heritage Resources, Western Libraries, Western Washington University, Bellingham, WA 98225-9103, USA (360-650-7534; heritage.resources@wwu.edu) and refer to the collection name and identifier. Any materials cited must be attributed to the Salish Sea Ecosystem Conference Records, University Archives, Heritage Resources, Western Libraries, Western Washington University.
Type
Text
Language
English
Format
application/pdf
Genetic and phylogenetic analysis of Vibrio parahaemolyticus reveals distinct differences in strains from the Pacific Northwest of the U.S.
Room 615-616-617
Genetic and phylogenetic analyses of Vibrio parahaemolyticus (Vp) strains isolated from the U.S. Pacific Northwest demonstrate that clinical isolates are genetically distinct from the environmental isolates. Several environmental isolates are clonally related to strains that have been responsible for Vp-related illnesses world-wide (the pandemic complex) but have not been responsible for illnesses in the Pacific Northwest. While both clinical and a significant proportion of environmental isolates encode one of the putative virulence markers, the thermostable direct hemolysin (tdh), clinical isolates also encoded a second virulence marker, the tdh-related hemolysin (trh). Our findings suggest that V. parahaemolyticus isolates from the Pacific Northwest encoding trh are more likely to be pathogenic than isolates encoding tdh alone.
