Senior Project Advisor
Josh Kaplan
Document Type
Project
Publication Date
Spring 2023
Keywords
Autism spectrum disorder, medical cannabis, cannabidiol, terpenes, brain-derived neurotrophic factor, BTBR mouse model, social behavior
Abstract
Cannabis-based medicines have emerged as a promising therapeutic for a variety of neuropsychiatric disorders, including autism spectrum disorder (ASD). This manuscript encompasses research investigating the application of the phytocannabinoid cannabidiol (CBD) in treating core symptoms of ASD. Chapter one includes a literature review of the neurodevelopmental etiology and current pharmacological strategies for ASD. The second chapter is a paper illustrating the prosocial effects of CBD and cannabis-inspired terpenes in our mouse model of ASD. The third chapter is a pilot study looking into the developmental pathology and adolescent exposure to CBD as an interventional strategy in our preclinical model. This work and continued research can inform cannabis-based treatments for ASD in the effort to improve quality of life and offer wider accessibility to medications for affected individuals.
Department
Behavioral Neuroscience
Recommended Citation
Staben, Jenika and Kaplan, Josh, "Developmental intervention with CBD on BDNF levels and prosocial behavior in a mouse model of autism spectrum disorder" (2023). WWU Honors College Senior Projects. 653.
https://cedar.wwu.edu/wwu_honors/653
Subjects - Topical (LCSH)
Autism spectrum disorders; Marijuana--Therapeutic use; Terpenes; Interpersonal relations
Type
Text
Rights
Copying of this document in whole or in part is allowable only for scholarly purposes. It is understood, however, that any copying or publication of this document for commercial purposes, or for financial gain, shall not be allowed without the author’s written permission.
Language
English
Format
application/pdf