Senior Project Advisor

Josh Kaplan

Document Type

Project

Publication Date

Spring 2023

Keywords

Autism spectrum disorder, medical cannabis, cannabidiol, terpenes, brain-derived neurotrophic factor, BTBR mouse model, social behavior

Abstract

Cannabis-based medicines have emerged as a promising therapeutic for a variety of neuropsychiatric disorders, including autism spectrum disorder (ASD). This manuscript encompasses research investigating the application of the phytocannabinoid cannabidiol (CBD) in treating core symptoms of ASD. Chapter one includes a literature review of the neurodevelopmental etiology and current pharmacological strategies for ASD. The second chapter is a paper illustrating the prosocial effects of CBD and cannabis-inspired terpenes in our mouse model of ASD. The third chapter is a pilot study looking into the developmental pathology and adolescent exposure to CBD as an interventional strategy in our preclinical model. This work and continued research can inform cannabis-based treatments for ASD in the effort to improve quality of life and offer wider accessibility to medications for affected individuals.

Department

Psychology

Subjects - Topical (LCSH)

Autism spectrum disorders; marijuana--Therapeutic use; Terpenes; Interpersonal relations

Type

Text

Rights

Copying of this document in whole or in part is allowable only for scholarly purposes. It is understood, however, that any copying or publication of this document for commercial purposes, or for financial gain, shall not be allowed without the author’s written permission.

Language

English

Format

application/pdf

Included in

Neurosciences Commons

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