Senior Project Advisor
Annelise Snyder
Document Type
Project - Campus-only Access
Publication Date
Spring 2025
Keywords
RIPK3, brain metastatic breast cancer, Rip, Rip Kinase three
Abstract
RIPK3 is known as a necroptosis inducing cell death protein, but in recent years has been shown to exhibit alternative pathways in the central nervous system. RIPK3 can cause pro inflammatory signaling in certain cells in the brain in a necroptosis-independent pathway. This is currently being studied in our lab in the context of brain metastatic breast cancer using murine and in vitro models, with focus on the phagocytic capabilities of microglia.
Department
Biology
Recommended Citation
Ragle, Selma and Snyder, Annelise, "RIPK3 signaling and effects" (2025). WWU Honors College Senior Projects. 989.
https://cedar.wwu.edu/wwu_honors/989
Type
Text
Rights
Copying of this document in whole or in part is allowable only for scholarly purposes. It is understood, however, that any copying or publication of this document for commercial purposes, or for financial gain, shall not be allowed without the author’s written permission.
Language
English
Format
application/pdf