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Date Permissions Signed

8-6-2018

Date of Award

Summer 2018

Document Type

Masters Thesis

Degree Name

Master of Science (MS)

Department

Chemistry

First Advisor

O'Neil, Gregory (Gregory W.)

Second Advisor

Vyvyan, James R.

Third Advisor

Antos, John M.

Abstract

Herein, we report new allylation reactions using ring-strained allylalkoxysiletanes. These reactions can achieve high yield and have high chemoselectivity, as evidenced by carefully designed substrates. Based on previous evidence, we propose that the reaction proceeds through an exchange mechanism, where first the alkoxy group of the siletane exchanges with the hydroxyl group of the substrate, followed by coordination of the substrate carbonyl to the siletane, and then intramolecular allylation of the carbonyl.

Type

Text

Keywords

silanes, carbonyl, allylation, chemoselective

DOI

https://doi.org/10.25710/kzb4-1r14

Publisher

Western Washington University

OCLC Number

1048259448

Subject – LCSH

Silane compounds; Carbonyl compounds; Nucleophilic reactions; Grignard reagents; Organic compounds--Synthesis; Catalysts

Format

application/pdf

Genre/Form

masters theses

Language

English

Rights

Copying of this document in whole or in part is allowable only for scholarly purposes. It is understood, however, that any copying or publication of this thesis for commercial purposes, or for financial gain, shall not be allowed without the author's written permission.

Included in

Chemistry Commons

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